Structural Characteristics and the Antioxidant and Hypoglycemic Activities of a Polysaccharide from Lonicera caerulea L. Pomace

In this study, a novel polysaccharide, LPP, was obtained from Lonicera caerulea L. pomace by ultrasonic-assisted heating and purified Sephadex G-100. The structural characteristics of LPP showed that the molecular weight (Mw) 8.53 × 104 Da; it mainly composed galacturonic acid, followed galactose; possessed characteristic functional groups polysaccharides; had an absence O-glycosidic bonds crystalline triple helix structures. Furthermore, exhibited favorable thermodynamic stability antioxidant, hypoglycemic, hypolipidemic activities in dose-dependent manner vitro, demonstrating can be used as agent to regulate glycolipid metabolism. Additionally, relationship between its bio-activities is discussed paper. results revealed RP, •OH, NO2− radicals synergistic promoting effects, polysaccharides with strong antioxidant ability may have excellent hypoglycemic effects. Collectively, these suggest has bio-activity, potential polysaccharide source.